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Name: Naglazyme
Generic Name: galsulfase (gal SUL fase)
Brand: Naglazyme
What:
Naglazyme is used to treat some of the symptoms of a genetic condition called Maroteaux-Lamy syndrome. Maroteaux-Lamy syndrome is also called mucopolysaccharidosis type VI, a mucopolysaccharide enzyme deficiency.
Naglazyme may improve walking and stair-climbing ability in people with this condition. However, it is not a cure for Maroteaux-Lamy syndrome.
Naglazyme may also be used for other purposes not listed in this medication guide.
Important:
Maroteaux-Lamy syndrome is a metabolic disorder in which the body lacks the enzyme needed to break down certain sugars and proteins. These substances can build up in the body, causing enlarged organs, abnormal bone structure, changes in facial features, breathing problems, heart problems, vision or hearing loss, and changes in mental or physical abilities.
Naglazyme may improve walking and stair-climbing ability in people with Maroteaux-Lamy syndrome. However, Naglazyme is not a cure for this condition. Some people receiving a Naglazyme injection have had a reaction to the infusion (when the medicine is injected into the vein). Tell your caregiver right away if you have a headache, fever or chills, skin rash, itching, nausea, vomiting, stomach pain, pain in your chest, trouble breathing, or if you feel like you might pass out when Naglazyme is injected.
Your name may need to be listed on a patient registry while you are using this medication. The purpose of this registry is to track the progression of this disorder and the effects that Naglazyme has on long-term treatment of Maroteaux-Lamy syndrome.
Before:
How:
Miss:
Contact your doctor if you miss an appointment for your Naglazyme injection.
Overdose:
Seek emergency medical attention if you think you have received too much of this medicine.
Symptoms of a Naglazyme overdose are not known.
Avoid:
Follow your doctor's instructions about any restrictions on food, beverages, or activity while you are receiving Naglazyme.
Effect:
Some people receiving a Naglazyme injection have had a reaction to the infusion (when the medicine is injected into the vein). Tell your caregiver right away if you have a headache, fever or chills, skin rash, itching, nausea, vomiting, stomach pain, pain in your chest, trouble breathing, or if you feel like you might pass out when Naglazyme is injected. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Less serious side effects may include:
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headache;
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joint pain;
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eye redness;
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nausea, vomiting, stomach pain, diarrhea;
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runny or stuffy nose, sore throat, cough, ear pain; or
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pain, redness, swelling, or other irritation where the medicine was injected.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.
Affect:
There may be other drugs that can interact with Naglazyme. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.
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